JAMA (Journal of the American Medical Association), November 24, 2004 - vol. 292, n° 20

Bauraind, I, Lopez-Lozano, J.M., Beyaert, A., Marchal, J.L., Yane, F., Goossens, H., Tulkens, P.M., Verbist, L.

Association between antibiotic sales and public campaigns for their appropriate use.

Two public campaigns for more rational use of antibiotics were organized in Belgium in 2000-2001 and 2001-2002 with a goal of reducing overuse and misuse of antibiotics in the community. We assessed their effectiveness with a time-series analysis that examined changes in antibiotic sales, accounting for the confounding effect of the seasonal variation of influenza-like illnesses.